Single-unit activity of the anterior Globus pallidus internus in Tourette patients and posterior Globus pallidus internus in dystonic patients
نویسندگان
چکیده
منابع مشابه
Failure of single-unit neuronal activity to differentiate globus pallidus internus and externus in Parkinson disease.
OBJECT The authors examine the validity of single-unit neuronal recordings as a method of differentiating the globus pallidus internus (GPi) from the GP externus (GPe) in Parkinson Disease. METHODS One hundred twenty-eight recordings of apparent single-unit activity used to help guide final electrode placement in eight patients who underwent pallidotomy were analyzed using sophisticated spike...
متن کاملOscillatory neural activity of anteromedial globus pallidus internus in Tourette syndrome.
Empirical data to support the use of deep brain stimulation (DBS) as a treatment for refractory Tourette syndrome (TS) is increasing (Saleh et al., 2012). Several clinical case series have been published, but few studies have examined the electrophysiology of the DBS target nuclei. We present the first electrophysiological description of simultaneously recorded single units and local field pote...
متن کاملNeuronal activity in the globus pallidus internus in patients with tics.
OBJECTIVE To explore the role of neuronal activity in the globus pallidus internus (GPi) in the generation of tic movements. METHODS 8 patients with Tourette's syndrome with medically intractable tics who underwent a unilateral pallidotomy for severe tics were studied. They ranged in age from 17 to 24 years; disease duration was 7-19 years. Microelectrode recording was performed in the GPi. T...
متن کاملDeep Brain Stimulation of the Globus Pallidus Internus in Patients with Intractable Tourette Syndrome: A 1-year Follow-up Study.
BACKGROUND Deep brain stimulation (DBS) has been a promising treatment for patients with refractory Tourette syndrome (TS) for more than a decade. Despite successful DBS treatment of TS in more than 100 patients worldwide, studies with a large patient sample and long-term follow-up assessments are still scarce. Accordingly, we investigated the clinical efficacy and safety of globus pallidus int...
متن کاملEffects of apomorphine on subthalamic nucleus and globus pallidus internus neurons in patients with Parkinson's disease.
This study examines the effect of apomorphine (APO), a nonselective D(1)- and D(2)-dopamine receptor agonist, on the firing activity of neurons in the subthalamic nucleus (STN) and internal segment of the globus pallidus (GPi) in patients with Parkinson's disease (PD). Single-unit microelectrode recordings were conducted in 13 patients undergoing implantation of deep brain stimulation electrode...
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ژورنال
عنوان ژورنال: Clinical Neurophysiology
سال: 2017
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2017.10.003